Journal article
Validation and recalibration of the Framingham cardiovascular disease risk models in an Australian Indigenous cohort
X Hua, R McDermott, T Lung, M Wenitong, A Tran-Duy, M Li, P Clarke
European Journal of Preventive Cardiology | SAGE PUBLICATIONS LTD | Published : 2017
Abstract
Background In Australia, clinical guidelines for primary prevention of cardiovascular disease recommend the use of the Framingham model to help identify those at high risk of developing the disease. However, this model has not been validated for the Indigenous population. Design Cohort study. Methods Framingham models were applied to the Well Person's Health Check (WPHC) cohort (followed 1998-2014), which included 1448 Aboriginal and Torres Strait Islanders from remote Indigenous communities in Far North Queensland. Cardiovascular disease risk predicted by the original and recalibrated Framingham models were compared with the observed risk in the WPHC cohort. Results The observed five- and 1..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The research reported in this presentation is a project of the Australian Primary Health Care Research Institute, which is supported under the Australian Government's Primary Health Care Research, Evaluation and Development Strategy. The information and opinions contained in it do not necessarily reflect the views or policy of the Australian Primary Health Care Research Institute or the Department of Health and Ageing. This study is supported by the Australia National Health and Medical Research Council project 'Building a simulation model to improve cardiovascular disease risk prediction and treatment for Indigenous Australians' (NHMRC/1107140). TL receives salary support as the HCF Research Foundation Postdoctoral Research Fellow.